Modafinil Dosage Guide for Narcolepsy and Shift Work Sleep Disorder
Modafinil Dosage Guide for Narcolepsy and Shift Work Sleep Disorder
Blog Article
Modafinil is a wake-promoting drug that has been shown to be effective in treating narcolepsy and shift work sleep disorder in placebo-controlled clinical trials. It is well tolerated and has low abuse potential.
Take 200 mg once daily in the morning or upon awakening. If you have shift work disorder, take it one hour before your first shift begins.
Dosage
Modafinil, also known as Provigil and Armodafinil, is a wakefulness-promoting agent that has been shown to improve wakefulness in people with excessive sleepiness associated with narcolepsy, shift work sleep disorder, or obstructive sleep apnea/hypopnea syndrome (in addition to the treatment of the underlying obstruction). It is available only by prescription and should be used as directed.
Modafinil 200 mg does not cause significant changes in blood pressure or heart rate and is generally well tolerated by patients with preexisting cardiovascular disease, although increased monitoring may be needed in some cases. Modafinil should be used with caution in patients with structural cardiac disease or severe hepatic impairment, and in those who have a history of psychosis/mania.
Take 1 tablet each day with or without food, as directed by your doctor. For best results, it is usually taken in the morning before starting your work shift if you are taking it for narcolepsy or OSA. However, it may be taken one hour before your shift if you are using it to treat SWD.
Side Effects
Modafinil, marketed under the brand name Provigil, is a prescription wakefulness medication. It can improve wakefulness in people with narcolepsy, obstructive sleep apnea (in conjunction with treatment of the underlying obstruction) or shift work sleep disorder (SWD).
Long-term Modafinil use, especially at high doses, can lead to psychological dependence. It can also cause a wide range of side effects, from gastrointestinal changes like nausea and diarrhea to cardiovascular changes like tachycardia and hypertension.
Because of its effect on brain chemicals, Modafinil can induce euphoria and mood changes in some people. This can lead to misuse and addiction, especially in people with a history of substance abuse problems. To reduce your risk of side effects, take modafinil exactly as prescribed by your doctor.
In addition, be sure to practice good sleep habits and continue treatment for your underlying condition. This will ensure that you are getting enough quality sleep while you are awake. Find The Recovery Village drug, alcohol and mental health rehab nearest you.
Precautions
Modafinil has been shown to improve wakefulness in patients with narcolepsy, obstructive sleep apnea (in addition to the treatment of the underlying obstruction), and shift work sleep disorder. It has also been shown to enhance cognitive function in healthy individuals and can be useful for people who have trouble concentrating.
Modalert Tablet is taken as a tablet to be taken by mouth one time per day, usually in the morning for narcolepsy and OSAHS. For shift work sleep disorder, the pill is usually taken about 1 hour before starting the shift. It is important to take this medication at the same time each day to help ensure consistency.
It is important to discuss with your doctor how the medication should be used and for how long. Modafinil is potentially habit-forming and should not be shared with others, especially with anyone who has a history of drug abuse or addiction. It is a controlled substance and must be kept in a secure location where it cannot be accessed by children or other people who might misuse it.
Interactions
Modafinil (also known as provigil) is a wakefulness-promoting medication that is used to treat narcolepsy, sleep apnea/hypopnea syndrome and shift work disorder. It works by inhibiting the reuptake of dopamine and norepinephrine in the ventrolateral preoptic nucleus of the hypothalamus and may increase orexinergic neurotransmitter levels in some patients.
It is an enantiomer of the wakefulness-promoting agent adrafinil (2-[(diphenylmethyl)sulfinyl]acetamide). It lacks the terminal amide hydroxy group of adrafinil, and thus is better tolerated than the racemic form of the drug.
Modafinil is a moderate inducer of the hepatic enzymes CYP2D6 and CYP3A4. It should be avoided with medications that are strong inhibitors of these enzymes, including certain antidepressants. When modafinil is coadministered with donepezil and other hepatic inhibitors, the elimination of donepezil is decreased; however, this does not affect the effectiveness of the medication. Doravirine; Lamivudine; Tenofovir Disoproxil Fumarate: (Moderate) Concurrent administration of modafinil and doravirine may result in decreased doravirine exposure, resulting in loss of virologic control. Report this page